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CPC 90% Purity Chondroitin Sulfate Bovine Sodium Verified by NSF-GMP with Drug Master File DMF
  • CPC 90% Purity Chondroitin Sulfate Bovine Sodium Verified by NSF-GMP with Drug Master File DMF

CPC 90% Purity Chondroitin Sulfate Bovine Sodium Verified by NSF-GMP with Drug Master File DMF

Place of Origin CHINA
Brand Name HS
Certification NSF-GMP
Model Number 90%
Product Details
Product:
Bovine Chondroitin Sulfate
Purity:
90% By CPC
Quality Certificate:
NSF-GMP
DMF:
Avialable
BSE:
Free Of BSE
GMO:
NONE GMO
High Light: 

sodium chondroitin sulfate

,

chondroitin sodium sulfate

Payment & Shipping Terms
Minimum Order Quantity
1KG-25KGS
Price
USD45.0/KG-USD55.0/KG
Packaging Details
25KG/Drum, 500KG/Pallet
Delivery Time
7 working days
Payment Terms
L/C, T/T
Supply Ability
28MT/Month
Product Description

CPC 90% Purity Bovine Chondroitin Sulfate Sodium Verfied by NSF-GMP with Drug Master File DMF

 

Bovine chondroitin sulfate sodium is a type of Mucopolysaccharides extracted from bovine cartialges, with 90% purity tested by CPC titration method. The bovine cartilages used for the production of chondroitin sulfate sodium are from health animals used for the human consumption. The cartilages are free of BSE/TSE, and Veterinary health certificates are available for each shipment.

 

The specification of bovine chondroitin sulfate sodium 90% by CPC Titration: 

 

Product: Chondroitin Sulfate sodium
Original Bovine(Terrestrial) Report Date 2017/02/17
Batch No.: HS1702038 Quantity: 1000KGS
Net Weight: 25KG/DRUM Gross weight: 27.5KG/DRUM
Manufacturing Date: 2017/02/10 Expiry Date: 2019/02/09

 

ITEMS


SPECIFICATIONS (TEST METHOD)

 

RESULT

Appearance White to off-white powder Pass
Identification Infra Red Confirmed (USP197K). Pass
  Sodium reaction (USP191) Positive
  The chromatogram of the enzymatically digested sample solution as obtained in the test for the limit of nonspecific disaccharides shows three main peaks corresponding to △DI-4S, △DI-6S,△DI-OS in the enzymatically digested standard solution. By peak area response, △ DI-4S is the most abundant, followed by the △ DI-6S, with △ DI-OS being the least abundant of the three  
Assay(ODB)
 
NLT90% (CPC Titration) 91.6%
Loss on drying
 
Less than12%(USP731) 8.0%
Nonespecific Dissaccharides NMT10% 7.2%
Protein
 
NMT6.0%(USP38) 4.9%
Sulfate
 
<0.24%(USP221) <0.24
Chloride
 
<0.5% (USP221) <0.5%
Heavy Metal
 
NMT20PPM (Method I USP231) Pass
PH (1%H2O solution)
 
5.5-7.5(USP791) 6.4
Specific Rotation
 
- 20°~ -30°(USP781S) -22.5°
Residue on Ignition
 
20%-30%(dry base)(USP281) 25.5%
OrganicVolatile Residual(Ethanol)
 
NMT0.5% (USP467) PASS
Clarity (5%H2O solution)
 
<0.35@420nm 0.22
Electrophoretic purity NMT2.0%(USP726) Pass
Bulk Density NLT 0.5g/ml Pass
Total Bacteria Count
 
<1000CFU/g (USP2021) Pass
Yeast & Mold
 
<100CFU/g (USP2021) Pass
Salmonella
 
Negative (USP2022) Negative
E.Coli
 
Negative (USP2022) Negative
Staphylococcus Aureus
 
Negative (USP2022) Negative
Enterobacteria
 
Negative in 1 gram (USP2022) Negative
Particle size 100% through 80 mesh Pass
Storage: 25kg/drum, keep in an airtight container, protected from light.

 

 

The benefits of Bovine Chondroitin Sulfate Sodium:

 

Chondroitin sulfate is a type of Mucopolysaccharides which is commonly found in the tissues of joints in both human and animals. It is considered as the building block for the tissues of human joints. Thus the benefits of chondroitin sulfate are :

 

1. Help to prevent the breakdow of cartilages in joints.

 

2. Help increase the fluids in the joints.

 

3. Relief the pain in the joints.

 

The application of Bovine Chondroitin Sulfate Sodium:

 

1. The main application of chondroitin sulfate is joint health dietary supplements including Tablets, Capsules, and powder form.

 

2. Some bovine chondroitin sulfate is used to produce OTC Drugs in some countries (USA excluded)

 

3. Bovine chondroitin sulfate could also be used to produce eye drops or Cosmetics.

 

The Manufacturing Production Flow Chart of bovine chondroitin sulfate:

 

 

 

Production Flow Chart of Bovine Chondroitin Sulfate

 

Bovine Cartilages

 

Pre-treatment(cartilages selecting and washing)

 

Boiling ( add NACL,boil for 5 hours at the temperature of 90℃)

 

Enzymolysis (add pancreatin, add NAOH to adjust the PH value to 8.5-9.0, boil for 6 hours at the temperature of 48℃-50℃

 

 

Flitration

 

First sedimentation(add ethanol to dissolve out the crude chondroitin sulfate)

 

Hydrolysis (add water and NACL,add NAOH to adjust PH value to about 9.0. Adjust temperature to 48℃-50℃

 

Flitration

 

Second sedimentation(add ethanol to dissolve out purified chondroitin sulfate

 

 

Dehydration (add ethanol to dehydrate the water out of chondroitin sulfate

 

 

Centrifugation (get rid of ethanol)

 

Drying

 

 

Milling and Sifting

 

Blending (No other materials are added, just mixing)

 

Packing and testing

 

Chondroitin sulfate in 25KGS/drum

 

 

The packing and Storage:

 

1. The packing is 25KG chondroitin sulfate is packed into Double PE bags and put into a fiber drum.

 

2. The chondroitin sulfate is extremely hygroscopic, avoid exposure to the air when unpacked the original package.

 

3. Packged into air tight PE bags,put into a fiber drum and then the drum in a cool and dry place, avoid direct sunshine exposure.

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